個(gè)人履歷
1、學(xué)歷背景:
1985.9-1989.7 延邊大學(xué)藥學(xué)院本科
1989.9-1992.6 延邊大學(xué)藥學(xué)院藥劑學(xué)碩士生
1996.8-1999.8 韓國江原大學(xué)藥學(xué)院藥劑學(xué),藥學(xué)博士
2、國外學(xué)習(xí)研究經(jīng)歷:
2000.12-2001.5 日本城西大學(xué)藥學(xué)部,訪問教授
2003.04-2004.5 日本京都藥科大學(xué)藥物動(dòng)力學(xué)研究室,博士后
2004.05-2004.2 日本天藤制藥株式會(huì)社創(chuàng)藥中心,主席研究員
3、工作經(jīng)歷:
1992.7-1996.7 延邊大學(xué)藥學(xué)院藥劑學(xué)教研室,助教、講師
1999.9-2003.4 延邊大學(xué)藥學(xué)院藥劑學(xué)教研室,副教授
2006.3-至今 蘇州大學(xué)藥學(xué)院藥劑學(xué)教研室,副教授、教授
研究方向
(1)生物大分子藥物的靶向給藥系統(tǒng)研究
(2)粘膜及經(jīng)皮給藥系統(tǒng)的研究與開發(fā)
(3)口服結(jié)腸定位釋藥制劑
科研課題
1. 國家自然科學(xué)基金面上項(xiàng)目(編號(hào):81173005),受體介導(dǎo)的溫敏性納米載體對(duì)siRNA體內(nèi)外傳遞及藥效的影響和機(jī)制研究,資助金額60萬,2012-2015,主持。
2. 國家自然科學(xué)基金面上項(xiàng)目(編號(hào):81173004),腫瘤細(xì)胞核靶向p53基因聚酰胺-胺聚合物遞送系統(tǒng)的研究,資助金額50萬,2012-2015,參與。
3. 國家“重大新藥創(chuàng)制”科技重大專項(xiàng)(編號(hào):2009ZX09502-009),中藥制劑物理改性技術(shù)研究,資助金額:36萬,2009-2011,蘇大主持。
4. 科技部國際合作項(xiàng)目(編號(hào):2009DFA31330),艾迪凍干粉針的制劑技術(shù)及藥代動(dòng)力學(xué),資助金額:90萬,2009-2011,蘇大主持。
5. 江蘇省高校自然科學(xué)基礎(chǔ)研究面上項(xiàng)目(編號(hào):08KJB350003), DEC-205介導(dǎo)樹突狀細(xì)胞靶向溫度敏感性納米載體的研究,資助金額:3萬,2008-2010,主持。
主要論文
1. Yanhang Ma, Lin Zhou, Haoquan Zheng, Lei Xing, Chenguang Li, Jinghao Cui* and Shunai Che*,pH-responsive mitoxantrone (MX) delivery using mesoporous silica nanoparticles (MSN),Journal of Materials Chemistry,2011, 21, 9483-9486. (1區(qū)雜志,IF2008: 4.65)
2. Qing-Ri Cao, Jing-Hao Cui, Jun Bom Park, Hyo-Kyung Han, Jaehwi Lee, Kyung Taek Oh, In choon Park, Beom-Jin Lee, Effect of food components and dosing times on the oral pharmacokinetics of nifedipine in rats, Int. J. Pharm., 2010, 396 (1-2): 39-44. (IF2008: 3.061)
3. Yu-Ling Li, Li Zhu, Zhaozhong Liu, Ru Cheng, Fenghua Meng, Jing-Hao Cui, Shun-Jun Ji, and Zhiyuan Zhong,Reversibly Stabilized Multifunctional Dextran Nanoparticles Efficiently Deliver Doxorubicin into the Nuclei of Cancer Cells,Angew. Chem. Int. Ed.,2009, 48, 9914u20139918.(IF2008: 10.879 )
4. Jing-Hao Cui, Qing-Ri Cao, Beom-Jin Lee, Enhanced delivery of bifidobacteria and fecal changes following the oral administration of gastric acid resistant bifidobacteria-loaded alginate poly-l-lysine microparticles in human volunteers, Drug Delivery, 2007,14: 265u2013271. (IF2008: 1.55)
5. Jing-Hao Cui, Qing-Ri Cao, Yun-Jae Choi and Beom-Jin Lee,Effect of Additives on the Viability of Bifidobacteria Loaded in Alginate Poly-l-lysine Microparticles During the Freeze-drying Process,Archives of Pharmacal Research, 29 (8), 707-711, 2006. (IF2008: 1.074)
6. Qing-Ri Cao, Yun-Woong Choi, Jing-Hao Cui and Beom-Jin Lee, Formulation, release characteristics and bioavailability of novel monolithic hydroxypropyl -methylcellulose matrix tablet containing acetaminophen, Journal of Controlled Release, 2005, 108 (2-3): 351-361. (IF2008: 5.69)
7. Qing-Ri Cao, Yun-Woong Choi,Jing-Hao Cui and Beom-Jin Lee, Effect of Solvents on Physical Properties and Release Characteristics of Monolithic Hydroxypropylmethylcellulose Matrix Granules and Tablets. Archives of Pharmacal Research, 2005 28:493-501. (IF2008: 1.074)
8. Jing-Hao Cui, Juhn-Su Goh, Seung-Yong Park, Pyeung-Hyeun Kim, and Beom-Jin Lee, Preparation and physical characterization of alginate poly-l-lysine microparticles using air-atomization technique, Drug Dev. Ind. Pharm. 27(4), 307-317, 2001(IF2008: 1.104)
9. Jing-Hao Cui, Juhn-Su Goh, Pyeung-Hyeun Kim, Suk-Ho Choi, Beom-Jin Lee Survival and stability of bifidobacteria loaded in alginate poly-l-lysine microparticles, Int. J. Pharm., 210 (2000) 51-59. (IF2008: 3.061)
10. Beom-Jin Lee, Jing-Hao Cui, Ok-Sun Park, Juhn Soo Goh, Tae Seok Ahn and Seung Yong Park, Stability and gastric acid resistance of Lactobacilli and Bifidobacteria in Commercial Yoghurts, Korean J. Microbiol., 35 (1), 89-93 (1999).
11. Beom-Jin Lee, Geun-Hong Min and Jing-Hao Cui, Correlation of drug solubility with trapping efficiency and release characteristics of alginate beads, Pharm. Pharmacol. Commun. 5: 85-89 (1999).
12. Beom-Jin Lee, Seung-Goo Ryu and Jing-Hao Cui, Formulation and release characteristics of hydroxypropyl methylcellulose matrix tablet Containing Melatonin, Drug Dev. Ind. Pharm., 25(4), 493-501 (1999).
13. Beom-Jin Lee, Seung-goo Ryu and Jing-Hao Cui, Controlled release of dual drug-loaded delivery hydroxypropyl-methylcellulose matrix tablet using aqueous-based polymeric coatings, Int. J. Pharm., 188,71-80,1999.
14. Beom-Jin Lee, Jing-Hao Cui, Keith A. Parrott, James W. Ayres and Robert L. Sack, Percutaneous absorption and model membrane variation of melatonin in aqueous-based propylene glycol and 2-hydroxypropyl-β-cyclodextrin vehicles, Arch. Pharm. Res. 21 (5), 503-507 (1998).
15. Beom-Jin Lee, Jing-Hao Cui, Tae-Wan Kim, Min-Young Heo, and Chong-Kook Kim, Biphasic release characteristics of dual drug-loaded alginate beads, Arch. Pharm. Res. 21 (6), 645-650 (1998).