人物經(jīng)歷
1986年牡丹江師范學(xué)院學(xué)士;
1989年中科院遺傳所碩士;
1999年密歇根州立大學(xué)博士。
研究方向
1、細(xì)菌病原體毒力基因的表達(dá)調(diào)控
2、耐藥發(fā)生與轉(zhuǎn)移的調(diào)控機(jī)制
3、病原菌與宿主互作機(jī)制
科研項(xiàng)目
1. 中國(guó)科學(xué)院“百人計(jì)劃”專項(xiàng),2004.01u20132007.12,資助金額:270萬(wàn)。
2. 國(guó)家“十一五”科技重大專項(xiàng)“艾滋病和病毒性肝炎等重大傳染病防治”子課題“結(jié)核病靶標(biāo)研究”,2008.10u20132011.05,資助金額:315萬(wàn)。
3. 中國(guó)科學(xué)院知識(shí)創(chuàng)新工程“結(jié)核分枝桿菌致病機(jī)制、快速診斷和新型藥物研究”,2009.6u20132011.05,資助金額:60萬(wàn)。
4. 國(guó)家自然科學(xué)基金“金黃色葡萄球菌非編碼小RNA的功能解析”,2010.01u20132012.12,資助金額:40萬(wàn)。
5. 國(guó)家自然科學(xué)基金“金黃色葡萄球菌KdpDE二元信號(hào)轉(zhuǎn)導(dǎo)系統(tǒng)對(duì)致病性的調(diào)控研究”,2011.01u20132013.12,資助金額:34萬(wàn)。
論文專著
Xiong, M., Y. Bao, X. Yang, Y. Wang, B. Sun, and J. Wang (2012). Lipase-sensitive polymeric triple-layered nanogel for "on-demand" drug delivery.J. Am. Chem. Soc. 134:4355-4362.
Xue, T., Y. You, F. Shang, and B. Sun (2012). Rot and Agr system modulate fibrinogen-binding ability mainly by regulatingclfBexpression inStaphylococcus aureusNCTC8325.Med. Microbiol. Immunol.201:81-92.
Xue, T., Y. You, D. Hong, H. Sun, and B. Sun (2011). TheStaphylococcus aureusKdpDE two-component system couples extracellular K sensing and Agr signaling to infection programming.Infect. Immun.79:2154-2167.
Zhao, L., T. Xue, F. Shang, H. Sun, and B. Sun (2010).Staphylococcus aureusAI-2 quorum sensing associates with the KdpDE two-component system to regulate capsular polysaccharide synthesis and virulence.Infect. Immun.78:3506-3515.
Tao, L., X. Wu, and B. Sun (2010). Alternative sigma factor σ modulates prophage integration and excision inStaphylococcus aureus.PLoS Pathog.6:e1000888.
Shang, F., T. Xue, H. Sun, L. Xing, S. Zhang, Z. Yang, L. Zhang, and B. Sun (2009). TheStaphylococcus aureusGGDEF domain-containing protein, GdpS, influences protein A gene expression in a cyclic diguanylic acid-independent manner.Infect. Immun.77:2849-2856.
Huang, J., B. Sun, and X. Zhang (2010).Shewanella xiamenensissp. nov., isolated from coastal sea sediment.Int. J. Syst. Evol. Microbiol. 60:1585-1589.
Huang, J., B. Sun, and X. Zhang (2010). Electricity generation at high ionic strength in microbial fuel cell by a newly isolatedShewanella marisflaviEP1.Appl. Microbiol. Biotechnol. 85:1141-1149.
Xue, T., L. Zhao, H. Sun, X. Zhou, and B. Sun (2009). LsrR binding-site recognition and regulatory characteristics inEscherichia coliAI-2 quorum sensing.Cell Res.19:1258-1268.
Wu, C. and B. Sun (2009). Identification of novel esterase from metagenomic library of Yangtze River.J. Microbiol. Biotechnol.19:187-193.
Chu, X., H. He, C. Guo, and B. Sun (2008). Identification of two novel esterases from a marine metagenomic library derived from South China Sea.Appl. Microbiol. Biotechnol.80:615-625.
Zhou, X., X. Meng, and B. Sun (2008). An EAL domain protein and cyclic AMP contribute to the interaction between the two quorum sensing systems inEscherichia coli.Cell Res.18:937-948.
Ju, X., L. Zhao, and B. Sun (2007). Nitrogen fixation by reductively dechlorinating bacteria.Environ. Microbiol.9:1078-1083.
Sun, B., B. M. Griffin, H. L. Ayala-del-Río, S. A. Hashsham, and J. M. Tiedje (2002). Microbial dehalorespiration with 1,1,1-trichloroethane.Science298:1023-1025.
Sun, B., J. R. Cole, and J. M. Tiedje (2001).Desulfomonile limimarissp. nov., an anaerobic dehalogenating bacterium from marine sediments.Int. J. Syst. Evol. Microbiol.51:365-371.
Sun, B., J. R. Cole, R. A. Sanford, and J. M. Tiedje (2000). Isolation and characterization ofDesulfovibrio dechloracetivoranssp. nov., a marine dechlorinating bacterium growing by coupling the oxidation of acetate to the reductive dechlorination of 2-chlorophenol.Appl. Environ. Microbiol.66:2408-2413.