研究領(lǐng)域
1、錐體蟲細(xì)胞周期調(diào)控的分子機制的研究；
2、錐體蟲SUMO系統(tǒng)的研究；
3、Kinesin家族蛋白成員在錐體蟲中的功能研究；
4、錐體蟲作為模式生物用以進(jìn)行高等真核細(xì)胞中核仁的研究。
科研項目
1：入選國家教育部“2005年新世紀(jì)優(yōu)秀人才支持計劃”；
2：主持承擔(dān)國家自然科學(xué)基金項目“錐體蟲動點相關(guān)蛋白Mad2,Skp1,TOG和中心體相關(guān)蛋白Spc97,Spc98在有絲分裂中的功能研究”；
3：主持承擔(dān)中國科學(xué)院知識創(chuàng)新工程重要方向項目子課題“錐體蟲作為生物模式用以進(jìn)行高等真核細(xì)胞中核仁的研究”。
代表論著
Xiaoming Tu, Praveen Kumar, Ziyin Li and Ching C. Wang （2006） An aurora kinase homologue is involved in regulating both mitosis and cytokinesis in Trypanosoma brucei. J. Biol Chem. 281:
Ziyin Li*, Xiaoming Tu*, and Ching C. Wang （2006）. Okadaic acid overcomes the blocked cell cycle caused by depleting Cdc2-related kinases in Trypanosoma brucei. Exp. Cell Res. 312:（*contributed equally）
Xiaoming Tu, Joel Mancuso, W. Zacheus Cande and Ching C. Wang （2005） Distinct Cytoskeletal Modulations and Mechanisms Regulating G1/S Transition between Two Life Stages of Trypanosoma brucei Cytoskeletal. Journal of Cell Science. 118:
Xiaoming Tu and Ching C. Wang （2005） Pairwise Knockdowns of cdc2-related Kinases （CRK） in Trypanosoma brucei Identified the CRKs for G1/S and G2/M Transitions and Demonstrated Distinctive Cytokinetic Regulations between Two Developmental Stages of the Organism. Eukaryotic Cell. 4:
Xiaoming Tu and Ching C. Wang （2005） Coupling of Posterior Cytoskeletal Morphogenesis to the G1/S Transition in the Trypanosoma brucei Cell Cycle. Mol. Biol. Cell. 16:97-105.
Xiaoming Tu and Ching C. Wang （2004） The involvement of two cdc2-related kinases （CRKs） in Trypanosoma brucei cell cycle regulation and the distinctive stage-specific phenotypes caused by CRK3 depletion. J. Biol. Chem. 279:
Xiaoming Tu, Jihui Wu, Yingqi Xu and Yunyu Shi （2001） Letter to the Editor: 1H, 13C and 15N resonance assignments and secondary structure of ADR6 DNA-binding domain. J. Biomol. NMR. 21:187-188.
Xiaoming Tu, Yazhong Xiao, Wangyong Zeng and Yunyu Shi （2000） Expression and purification of a recombinant DNA-binding domain of ADR6 protein from Escherichia coli and its secondary structure characterization. Biochim. Biophys. Acta. 1481:167-174.
He Zhang, Yuzhi Hong, Yazhong Xiao, Jing Yuan, Xiaoming Tu and Xiaoqing Zhang （2006） Efficient production of laccases by Trametes sp. AH28-2 in cocultivation with a Trichoderma strain. Applied Microbiology and Biotechnology. 73：89-94.
Yazhong Xiao, Xiaoming Tu, J. Wang, M. Zhang, Quan Cheng, Wangyong Zeng, Yunyu Shi （2003） Purification, molecular characterization and reactivity with aromatic compounds of a laccase from basidiomycete Trametes sp. strain AH28-2. Appl. Microbiol. Biotechnol. 60:700-707.
Wangyong Zeng, Xuecheng Zhang, Xiaoming Tu, Shouhong Guang, Yazhong Xiao and Yunyu Shi （2001） Expression and Purification of the DNA-Binding Domain of the Human Transcription Factor E2F1. Protein Expr. and Purif. 21:99-104.
