人物簡介
金長江，男，博士，副教授，碩士生導(dǎo)師。
2005年畢業(yè)于中國科學(xué)技術(shù)大學(xué)并獲生物學(xué)博士學(xué)位。其后在合肥微尺度物質(zhì)科學(xué)國家實驗室從事博士后研究。2009年作為優(yōu)秀人才引進被聘為中國科學(xué)技術(shù)大學(xué)生命科學(xué)學(xué)院副教授。廣泛從事了細(xì)胞膜與細(xì)胞骨架動力學(xué)、細(xì)胞有絲分裂調(diào)控及蛋白質(zhì)修飾調(diào)控的生物學(xué)研究。自2003年起，發(fā)表SCI 文章20余篇，其中部分刊登在Oncogene, J. Biol. Chem.等國際知名學(xué)術(shù)期刊上。
研究興趣
1) 蛋白質(zhì)翻譯后修飾調(diào)控
2) 細(xì)胞周期調(diào)控
3) 膜泡運輸
代表性論文
1. Yu J, Lan J, Wang C, Wu Q, Zhu Y, Lai X, Sun J, Jin C?, Huang H?. PML3 interacts with TRF1 and is essential for ALT-associated PML bodies assembly in U2OS cells. Cancer Lett. 2009 Nov 7. [Epub ahead of print] (? Corresponding author)
2.Yuan K, Li N, Jiang K, Zhu T, Huo Y, Wang C, Lu J, Shaw A, Thomas K, Zhang J, Mann D, Liao J, Jin C?, Yao X?. PinX1 is a novel microtubule-binding protein essential for accurate chromosome segregation. J Biol Chem 2009 284(34):23072-23082 (? Corresponding author)
3.Yuan K, Li N, Huo Y, Yan F, Yang Y, Ward T, Jin C?, Yao X?. Recruitment of separase to mitotic chromosomes is regulated by Aurora B. Cell Cycle 2009 8(9):1433-43. (? Corresponding author)
4.Du J, Cai X, Yao J, Ding X ?, Wu Q, Pei S, Jiang K, Zhang Y, Wang W, Shi Y, Lai Y, Shen J, Teng M, Huang H, Fei Q, Reddy ES, Zhu J, Jin C ?, and Yao X. ? 2008. The mitotic checkpoint kinase NEK2A regulates kinetochore microtubule attachment stability. Oncogene 2008 27 (29): 4107-4114. (? Corresponding author)
5.Cheng Z, Ke Y, Ding X, Wang F, Wang H, Wang W, Ahmed K, Liu Z, Xu Y, Aikhionbare F, Yan H, Liu J, Xue Y, Yu J, Powell M, Liang S, Wu Q, Reddy SE, Hu R, Huang H, Jin C?, and Yao X. ? 2008.Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response. Oncogene 27, 931-941. (? Corresponding author)
6. Yu J, Lan J, Zhu Y, Li X, Lai X, Xue Y, Jin C?, and Huang H. ? The E3 ubiquitin ligase HECTD3 regulates ubiquitination and degradation of Tara. 2008. Biochem Biophys Res Commun367, 805u2013812. (? Corresponding author)
7.Liu D, Ding X, Du J, Cai X, Huang Y, Ward T, Yang Y, Hu R, Jin C?, and Yao X. ? 2007. Human NUF2 Interacts with Centromere-associated Protein E and is essential for a stable spindle microtubule-kinetochore attachment. J Biol Chem 282, 21415-21424. (? Corresponding author)
8.Jin C, Cai X, Ma H, Xue Y, Yao J, and Yao X. 2007. An efficient site-directed mutagenesis method for ColE1-type ori plasmid. Analytical Biochemistry 363, 151u2013153.
9.Jin C, Ge L, Ding X, Chen Y, Zhu H, Ward T, Wu F, Cao X, Wang Q, Yao X. 2006. PKA-mediated protein phosphorylation regulates Ezrin-WWOX interaction. Biochem Biophys Res Commun341, 784-791.
10.Jin C, Zhang Y, Zhu H, Ahmed K, Fu C, and Yao X. 2005. Human Yip1A specifies the localization of Yif1 to the Golgi apparatus. Biochem Biophys Res Commun334, 16u201322.