人物經(jīng)歷
香港城市大學(xué)獲理學(xué)博士學(xué)位 (2000)。于加拿大McMaster大學(xué)生物系做博士后研究 (Post-doctoral Fellow, 2001-2003),在香港城市大學(xué)海岸污染與環(huán)境保護研究中心工作 (Research Fellow, 2003-2004)。任研究員,博士研究生導(dǎo)師,環(huán)境毒理組組長。擔任: 環(huán)境化學(xué)、生態(tài)毒理學(xué)報、Journal of Environmental Sciences、Aquatic Toxicology等雜志編委,是中國化學(xué)會環(huán)境化學(xué)專業(yè)委員會委員。獲得2011和2016年度中國科學(xué)院優(yōu)秀研究生指導(dǎo)教師獎以及2012年度中國科學(xué)院朱李月華優(yōu)秀教師獎。
研究方向
環(huán)境毒理學(xué)
科研項目
( 1 )典型持久性有機污染物的環(huán)境過程與毒性效應(yīng), 參與,國家級,2009-01--2012-12
( 2 )水環(huán)境中孕激素類污染物對斑馬魚的內(nèi)分泌干擾效應(yīng)和分子機制, 主持,國家級,2013-01--2016-12
( 3 )有機農(nóng)藥和含銅、鋅無機農(nóng)藥的協(xié)同毒性作用機理, 參與,國家級,2013-01--2017-12
( 4 )氣體過飽和、有機污染物和重金屬等關(guān)鍵環(huán)境因子的魚類生物學(xué)效應(yīng)研究, 參與,研究所(學(xué)校),2013-01--2015-12
( 5 )典型支流庫灣的水環(huán)境背景調(diào)查與生態(tài)安全評估, 參與,研究所(學(xué)校),2013-01--2015-12
( 6 )電子廢棄物溴代阻燃劑和重金屬復(fù)合污染的人體暴露評價技術(shù)研究, 參與,國家級,2013-01--2016-12
( 7 )污染物的內(nèi)分泌干擾效應(yīng)與發(fā)育毒性機制, 主持,部委級,2014-06--2018-06
( 8 )納米TiO2與典型有機污染物的復(fù)合暴露對斑馬魚的毒性效應(yīng), 主持,國家級,2016-01--2019-12
( 9 )新興溴代阻燃劑的水環(huán)境暴露、毒性效應(yīng)及分子機制, 主持,國家級,2018-01--2022-12
( 10 )典型養(yǎng)殖系統(tǒng)對自然水域生態(tài)系統(tǒng)的影響機理, 主持,國家級,2018-12--2022-12
專家類別
百人
社會任職
2018-12-01-任Chemosphere, 雜志編委
2017-05-05-任aquatic toxicology, 雜志編委
2015-01-01-2016-12-31,雜志編委,
2014-06-09-任雜志編委,
2010-03-01-2013-05-01,科學(xué)通報、環(huán)境化學(xué)、生態(tài)毒理學(xué)報, 編委
代表論著
論文
1. Wang Q, Chen Q, Zhou P, Li W, Wang J, Huang C, Wang X, Lin K, Zhou B*. Bioconcentration and metabolism of BDE-209 in the presence of titanium dioxide nanoparticles and impact on the thyroid endocrine system and neuronal development in zebrafish larvae. Nanotoxicology (in press).
2. Guo Y, Zhou B*, 2013. Thyroid endocrine system disruption by pentachlorophenol: an in vitro and in vivo assay. Aquatic Toxicology
3. Wang X, Yang Y, Zhang L, Ma Y, Han J, Yang L, Zhou B*, 2013. Endocrine disruption by di-(2-ethylhexyl)-phthalate in Chinese rare minnow (Gobiocypris rarus). Environmental Toxicology & Chemistry
4. Chen L, Huang Y, Huang C, Hu B, Hu C, Zhou B*, 2013. Acute exposure to DE-71 causes alterations in visual behavior in zebrafish larvae. Environmental Toxicology & Chemistry
5. Wang Q, Liang K, Liu J, Yang L, Guo Y, Liu C*, Zhou B*, 2013. Exposure of zebrafish embryos/larvae to TDCPP alters concentrations of thyroid hormones and transcriptions of genes involved in the hypothalamic-pituitary-thyroid axis. Aquatic Toxicolo
6. Chen L, Huang C, Hu C, Ke Y, Yang L, Zhou B*, 2012. Acute exposure to DE-71: Effects on locomotor behavior and developmental neurotoxicity in zebrafish larvae. Environmental Toxicology & Chemistry
7. Chen L, Yu K, Huang C, Yu L, Zhu B, PKS Lam, JCW Lam*, Zhou B*, 2012. Prenatal transfer of polybrominated diphenyl ethers (PBDEs) results in developmental neurotoxicity in zebrafish larvae. Environmental Science & Technology
8. Ma Y, Han J, Guo Y, Lam PKS, Wu RSS, Giesy JP, Zhang X, Zhou B*, 2012. Disruption of endocrine function in in vitro H295R cell-based and in in vivo assay in zebrafish by 2,4-dichlorophenol. Aquatic Toxicology
9. Chen Q, Yu L, Yang L, Zhou B*, 2012. Bioconcentration and metabolism of decabromodiphenyl ether (BDE-209) result in thyroid endocrine disruption in zebrafish larvae. Aquatic Toxicology
10. Chen L, Hu C, Huang C, Wang Q, Wang X, Yang L, Zhou B*, 2012. Alterations in retinoid status after long-term exposure to PBDEs in zebrafish (Danio rerio). Aquatic Toxicology
11. Ma Y, Han J, Guo Y, Lam PKS, Wu RSS, Giesy JP, Zhang X, Zhou B*, 2011. Modulation of steroidogenic gene expression and hormone synthesis in H295R cells exposed to PCP and TCP. Toxicology
12. Yu L, Lam JCW, Guo Y, Wu RSS, Lam* PKS, Zhou B*, 2011. Parental transfer of PBDEs and thyroid endocrine disruption in zebrafish. Environmental Science & Technology
13. Liu C, Zhang X, Deng J, Hecker M, AL-Khedhairy A, Giesy JP, Zhou B*, 2011. Effects of prochloraz or propylthiouracil on the cross-talk between the HPG, HPA and HPT Axes in zebrafish. Environmental Science & Technology
14. Liu C, Zhang X, Chang H, Jones P, Wiseman S, Naile J, Hecker M, Giesy JP, Zhou B*, 2010. Effects of fluorotelomer alcohol 8:2 FTOH on steroidogenesis in H295R cells: Targeting the cAMP signaling cascade. Toxicology & Applied Pharmacology
15. Shi X, Zhou B*, 2010. The role of Nrf2 and MAPK pathways in PFOS-induced oxidative stress in zebrafish embryos. Toxicological Sciences
16. Yu L, Deng J, Shi X, Liu C, Yu K, Zhou B*, 2010. Exposure to DE-71 alters thyroid hormone levels and gene transcription in the hypothalamicu2013pituitaryu2013thyroid axis of zebrafish larvae. Aquatic Toxicology
17. Liu C, Deng J, Yu L, Ramesh M, Zhou B*, 2010. Endocrine disruption and reproductive impairment in zebrafish by exposure to 8:2 fluorotelomer alcohol. Aquatic Toxicology
18. Deng J, Liu C, Yu L, Zhou B*, 2010. Chronic exposure to environmental levels of tribromophenol impairs zebrafish reproduction. Toxicology & Applied Pharmacology
19. Shi X, Yeung LWY, Lam PKS, Wu RSS, Zhou B*, 2009. Protein Profiles in Zebrafish (Danio rerio) Embryos Exposed to PFOS. Toxicological Sciences
20. Deng J, Yu L, Liu C, Yu K, Shi X, Yeung L, Lam PKS, Wu RSS, Zhou B*, 2009. Hexabromocyclododecane-induced developmental toxicity and apoptosis in zebrafish embryos. Aquatic Toxicology
21. Liu C, Yu L, Deng J, Lam PKS, Wu RSS, Zhou B*, 2009. Waterborne exposure to fluorotelomer alcohol 6:2 FTOH alters plasma sex hormone and gene transcription in the hypothalamicu2013pituitaryu2013gonadal (HPG) axis of zebrafish. Aquatic Toxicology
22. Shi X, Liu C, Wu G, Zhou B*, 2009. Waterborne exposure to PFOS causes disruption of the hypothalamus-pituitary- thyroid axis in zebrafish larvae. Chemosphere
23. Du Y, Shi X, Liu C, Yu K, Zhou B*, 2009. Chronic effects of waterborne PFOS exposure on growth, survival and hepatotoxicity in zebrafish: a partial life-cycle test. Chemosphere
24. Yu K, He Y, Yeung LWY, Lam PKS, Wu RSS, Zhou B*, 2008. DE-71-induced apoptosis involving intracellular calcium and the Bax-mitochondria-caspase protease pathway in human neuroblastoma cells in vitro. Toxicological Sciences
25. Shi X, Du Y, Lam PKS, Wu RSS, Zhou B*, 2008. Developmental toxicity and alteration of gene expression in zebrafish embryos exposed to PFOS. Toxicology & Applied Pharmacology
26. Liu C, Du Y, Zhou B*, 2007. Evaluation of estrogenic activities and mechanism of action of perfluorinated chemicals determined by vitellogenin induction in primary cultured tilapia hepatocytes. Aquatic Toxicology
27. Ding L, Murphy MB, He Y, Xu Y, Yeung LWY, Wang J, Zhou B*, Lam PKS, Wu RSS, Giesy JP, 2007. Effects of brominated flame retardants and brominated dioxins on steroidgenesis in H295R cells. Environmental Toxicology & Chemistry
28. Liu C, Yu K, Shi X, Wang J, Lam PKS, Wu RSS, Zhou B*, 2007. Induction of oxidative stress and apoptosis by PFOS and PFOA in primary cultured hepatocytes of freshwater tilapia (Oreochromis niloticus). Aquatic Toxicology
29. Zhou B*, Liu C, Wang J, Lam PKS, Wu RSS, 2006. Primary cultured cells as sensitive in vitro model for assessment of toxicants-comparison to hepatocytes and gill epithelia. Aquatic Toxicology
著作
( 1 )持久性有機污染物的內(nèi)分泌干擾效應(yīng),科學(xué)出版社,2018-06,第1作者