個(gè)人簡(jiǎn)歷
有機(jī)化學(xué)博士,北京大學(xué)藥學(xué)院副教授。
1993-1997 理學(xué)學(xué)士,蘭州大學(xué)化學(xué)系應(yīng)用化學(xué)專業(yè);1997-2002 理學(xué)博士,蘭州大學(xué)化學(xué)系有機(jī)化學(xué)專業(yè) (導(dǎo)師:涂永強(qiáng));2002-2007 博士后,法國(guó)國(guó)家科學(xué)研究中心,天然產(chǎn)物化學(xué)研究所(導(dǎo)師:祝介平);從2007年至今任北京大學(xué)藥學(xué)院副教授
研究領(lǐng)域
具有重要生物活性天然產(chǎn)物的全合成及仿生合成;生物活性天然產(chǎn)物的結(jié)構(gòu)改造以及構(gòu)效關(guān)系研究;基于天然產(chǎn)物小分子探針的發(fā)現(xiàn);有機(jī)合成新方法、新策略的研究。
學(xué)術(shù)成就
2009 新世紀(jì)優(yōu)秀人才支持計(jì)劃
2008 第十一屆中國(guó)藥學(xué)會(huì)-施維雅青年藥物化學(xué)獎(jiǎng)
2002 甘肅省科技進(jìn)步獎(jiǎng), 一等獎(jiǎng)
人物榮譽(yù)
2019年8月2日,賈彥興入選2019年度國(guó)家杰出青年科學(xué)基金建議資助項(xiàng)目申請(qǐng)人名單。
發(fā)表論文
1. “Stereocontrolled and Efficient Total Synthesis of (u2013)-Stephanotic Acid Methyl Ester and (u2013)-Celogentin C”, Weimin Hu, Fengying Zhang, Zhengren Xu, Qiang Liu, Yuxin Cui, Yanxing Jia*. Org. Lett. 2010, 12, 956-959.
2. “Water-Controlled Regioselectivity of Pd-Catalyzed Domino Reaction Involving a Cu2013H Activation Process: Rapid Synthesis of Diverse Carbo- and Heterocyclic Skeletons”, Zhiyao Lu, Chunmei Hu, Jiajie Guo, Jing Li, Yuxin Cui, Yanxing Jia*. Org. Lett. 2010, 12, 480-483.
3. “Formal synthesis of semiaquilegin A”, Jing Li, Yong Jiang, Qingjiang Li, Qiang Xiao, Yanxing Jia*, Pengfei Tu*. Tetrahedron Lett. 2010, 51, 1121-1123.
4. “Palladium-Catalyzed Synthesis of Tryptamines and Tryptamine Homologues: Synthesis of Psilocin”, Chunmei Hu, Hua Qin, Yuxin Cui, Yanxing Jia*. Tetrahedron,2009, 65, 9075-9080.
5. "Efficient Total Synthesis of (u2013)-cis-Clavicipitic Acid”, Zhengren Xu, Qingjiang Li, Lihe Zhang, Yanxing Jia*. J. Org. Chem. 2009, 74, 6859-6862."
6.“Total Synthesis of (-)-Incarvilline and (-)-Incarvillateine”, Fengying Zhang, Yanxing Jia*. Tetrahedron 2009, 65, 6840-6843.
7.“Palladium-Catalyzed Indole and Azaindole synthesis by Direct Annulation of Electron-Poor o-Chloroanilines and Chloroaminopyridines with Aldehydes”, Zhengren Xu, Weimin Hu, Fengying Zhang, Qingjiang Li, Zhiyao Lü, Lihe Zhang, Yanxing Jia*. Synthesis 2008, 3981-3987.
8.“Synthesis of Diastereomers of Complestatin, and Chloropeptin, High Substrate-dependent Atropstereoselectivity of Intramolecular Suzuki-Miyaura Reaction”, Yanxing Jia, Michèle Bois-Choussy, Jieping Zhu*. Angew. Chem. Int. Ed. 2008, 47, 4167-4172.
9.“Synthesis of DEFG Ring of Complestatin and Chloropeptin I: Highly Atropdiastereoselective Macrocyclization by Intramolecular Suzuki-Miyaura Reaction”, Yanxing Jia, Michèle Bois-Choussy, Jieping Zhu*. Org. Lett. 2007, 9, 2401-2404.
10.“Design and Synthesis of Simple Macrocycles Active Against Vancomycin-resistant Enterococci (VRE)”, Yanxing Jia, Nianchun Ma, Zuosheng Liu, Michèle Bois-Choussy, Eduardo Gonzalez-Zamora, Adriano Malabarba, Cristina Brunati, Jieping Zhu*. Chem. Eur. J. 2006, 12, 5334-5351.
11.“Palladium-Catalyzed, Modular Synthesis of Highly Functionalized Indoles and Tryptophans by Direct Annulation of Substituted o-Haloanilines and Aldehydes”, Yanxing Jia, Jieping Zhu*. J. Org. Chem. 2006, 71, 7826-7834.
12.“Synthetic Studies of the HIV-1 Protease Inhibitive Didemnaketals: Stereocontrolled Synthetic Approach to the Key Mother Spiroketals”, Yanxing Jia, Bin Wu, Xin Li, Shikuo Ren, Yongqiang Tu,* Albert S. C. Chan, William Kitching. Org. Lett. 2001, 3, 847-849.